16 research outputs found

    Attitudes of Undergraduate Social Work Students Toward Interprofessional Health Care Practice and Interprofessional Health Care Education

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    In 2005, the Centre for Collaborative Health Professional Education at Memorial University in Canada commenced an inquiry into the interprofessional education (IPE) of social work students. In the 2005/2006 academic year, undergraduate social work students were introduced to an IPE program at Memorial University for the first time. This interdisciplinary initiative brought together students from pharmacy, nursing, medicine, and social work to develop and encourage interprofessional educational activities with the purpose of increasing collaborative patient-centered practice competencies of students and professionals (Sharpe & Curran, 2006). In the subsequent three academic years (2005/2006, 2006/2007, 2007/2008) Bachelor of Social Work (BSW) students explored a variety of IPE modules. This paper summarizes the available literature on the topic of IPE and reports on data collected from three cohorts of undergraduate social work students regarding their attitudes toward interdisciplinary team practice. Data collected are in relation to the Health and Wellbeing of Children module, one of the five module topics in which these students participated over the three-year period. It is proposed that by understanding student attitudes as they are evidenced at this early stage of professional development, valuable information will be provided to educators to inform best practices in the teaching and learning of interprofessional practice skills within the discipline of social work. Finally, the authors provide suggested directions for future research

    Structural Social Work Lens: A View of Youth Engagement in the Social Policy Life of their Communities

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    Presented through a structural social work lens, this paper is a description and analysis of an action research project designed to explore factors that encourage or impede the engagement of youth in the social policy life of their communities. The project was conceptualized in a geographic region characterized by the erosion of community sustainability due to social economic disadvantage and out migration. The project aimed to strengthen communities by enhancing participation of youth in social policy development. It utilized a workshop designed and delivered by youth for youth and the development a Social Policy Action Plan (SPAP) to address a policy issue of concern in youth’s local community. Principles of structural social work, with particular attention to power sharing, unmasking the structures, collective consciousness, transformation of power/political and personal change, social action and community capacity building are applied as a lens to explore this project

    Safety, immunogenicity, and reactogenicity of BNT162b2 and mRNA-1273 COVID-19 vaccines given as fourth-dose boosters following two doses of ChAdOx1 nCoV-19 or BNT162b2 and a third dose of BNT162b2 (COV-BOOST): a multicentre, blinded, phase 2, randomised trial

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    The James Webb Space Telescope Mission

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    Twenty-six years ago a small committee report, building on earlier studies, expounded a compelling and poetic vision for the future of astronomy, calling for an infrared-optimized space telescope with an aperture of at least 4m4m. With the support of their governments in the US, Europe, and Canada, 20,000 people realized that vision as the 6.5m6.5m James Webb Space Telescope. A generation of astronomers will celebrate their accomplishments for the life of the mission, potentially as long as 20 years, and beyond. This report and the scientific discoveries that follow are extended thank-you notes to the 20,000 team members. The telescope is working perfectly, with much better image quality than expected. In this and accompanying papers, we give a brief history, describe the observatory, outline its objectives and current observing program, and discuss the inventions and people who made it possible. We cite detailed reports on the design and the measured performance on orbit.Comment: Accepted by PASP for the special issue on The James Webb Space Telescope Overview, 29 pages, 4 figure

    Safety, immunogenicity, and reactogenicity of BNT162b2 and mRNA-1273 COVID-19 vaccines given as fourth-dose boosters following two doses of ChAdOx1 nCoV-19 or BNT162b2 and a third dose of BNT162b2 (COV-BOOST): a multicentre, blinded, phase 2, randomised trial

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    Background Some high-income countries have deployed fourth doses of COVID-19 vaccines, but the clinical need, effectiveness, timing, and dose of a fourth dose remain uncertain. We aimed to investigate the safety, reactogenicity, and immunogenicity of fourth-dose boosters against COVID-19.Methods The COV-BOOST trial is a multicentre, blinded, phase 2, randomised controlled trial of seven COVID-19 vaccines given as third-dose boosters at 18 sites in the UK. This sub-study enrolled participants who had received BNT162b2 (Pfizer-BioNTech) as their third dose in COV-BOOST and randomly assigned them (1:1) to receive a fourth dose of either BNT162b2 (30 µg in 0·30 mL; full dose) or mRNA-1273 (Moderna; 50 µg in 0·25 mL; half dose) via intramuscular injection into the upper arm. The computer-generated randomisation list was created by the study statisticians with random block sizes of two or four. Participants and all study staff not delivering the vaccines were masked to treatment allocation. The coprimary outcomes were safety and reactogenicity, and immunogenicity (antispike protein IgG titres by ELISA and cellular immune response by ELISpot). We compared immunogenicity at 28 days after the third dose versus 14 days after the fourth dose and at day 0 versus day 14 relative to the fourth dose. Safety and reactogenicity were assessed in the per-protocol population, which comprised all participants who received a fourth-dose booster regardless of their SARS-CoV-2 serostatus. Immunogenicity was primarily analysed in a modified intention-to-treat population comprising seronegative participants who had received a fourth-dose booster and had available endpoint data. This trial is registered with ISRCTN, 73765130, and is ongoing.Findings Between Jan 11 and Jan 25, 2022, 166 participants were screened, randomly assigned, and received either full-dose BNT162b2 (n=83) or half-dose mRNA-1273 (n=83) as a fourth dose. The median age of these participants was 70·1 years (IQR 51·6–77·5) and 86 (52%) of 166 participants were female and 80 (48%) were male. The median interval between the third and fourth doses was 208·5 days (IQR 203·3–214·8). Pain was the most common local solicited adverse event and fatigue was the most common systemic solicited adverse event after BNT162b2 or mRNA-1273 booster doses. None of three serious adverse events reported after a fourth dose with BNT162b2 were related to the study vaccine. In the BNT162b2 group, geometric mean anti-spike protein IgG concentration at day 28 after the third dose was 23 325 ELISA laboratory units (ELU)/mL (95% CI 20 030–27 162), which increased to 37 460 ELU/mL (31 996–43 857) at day 14 after the fourth dose, representing a significant fold change (geometric mean 1·59, 95% CI 1·41–1·78). There was a significant increase in geometric mean anti-spike protein IgG concentration from 28 days after the third dose (25 317 ELU/mL, 95% CI 20 996–30 528) to 14 days after a fourth dose of mRNA-1273 (54 936 ELU/mL, 46 826–64 452), with a geometric mean fold change of 2·19 (1·90–2·52). The fold changes in anti-spike protein IgG titres from before (day 0) to after (day 14) the fourth dose were 12·19 (95% CI 10·37–14·32) and 15·90 (12·92–19·58) in the BNT162b2 and mRNA-1273 groups, respectively. T-cell responses were also boosted after the fourth dose (eg, the fold changes for the wild-type variant from before to after the fourth dose were 7·32 [95% CI 3·24–16·54] in the BNT162b2 group and 6·22 [3·90–9·92] in the mRNA-1273 group).Interpretation Fourth-dose COVID-19 mRNA booster vaccines are well tolerated and boost cellular and humoral immunity. Peak responses after the fourth dose were similar to, and possibly better than, peak responses after the third dose

    Breast cancer management pathways during the COVID-19 pandemic: outcomes from the UK ‘Alert Level 4’ phase of the B-MaP-C study

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    Abstract: Background: The B-MaP-C study aimed to determine alterations to breast cancer (BC) management during the peak transmission period of the UK COVID-19 pandemic and the potential impact of these treatment decisions. Methods: This was a national cohort study of patients with early BC undergoing multidisciplinary team (MDT)-guided treatment recommendations during the pandemic, designated ‘standard’ or ‘COVID-altered’, in the preoperative, operative and post-operative setting. Findings: Of 3776 patients (from 64 UK units) in the study, 2246 (59%) had ‘COVID-altered’ management. ‘Bridging’ endocrine therapy was used (n = 951) where theatre capacity was reduced. There was increasing access to COVID-19 low-risk theatres during the study period (59%). In line with national guidance, immediate breast reconstruction was avoided (n = 299). Where adjuvant chemotherapy was omitted (n = 81), the median benefit was only 3% (IQR 2–9%) using ‘NHS Predict’. There was the rapid adoption of new evidence-based hypofractionated radiotherapy (n = 781, from 46 units). Only 14 patients (1%) tested positive for SARS-CoV-2 during their treatment journey. Conclusions: The majority of ‘COVID-altered’ management decisions were largely in line with pre-COVID evidence-based guidelines, implying that breast cancer survival outcomes are unlikely to be negatively impacted by the pandemic. However, in this study, the potential impact of delays to BC presentation or diagnosis remains unknown

    Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study

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    Introduction: The multiorgan impact of moderate to severe coronavirus infections in the post-acute phase is still poorly understood. We aimed to evaluate the excess burden of multiorgan abnormalities after hospitalisation with COVID-19, evaluate their determinants, and explore associations with patient-related outcome measures. Methods: In a prospective, UK-wide, multicentre MRI follow-up study (C-MORE), adults (aged ≥18 years) discharged from hospital following COVID-19 who were included in Tier 2 of the Post-hospitalisation COVID-19 study (PHOSP-COVID) and contemporary controls with no evidence of previous COVID-19 (SARS-CoV-2 nucleocapsid antibody negative) underwent multiorgan MRI (lungs, heart, brain, liver, and kidneys) with quantitative and qualitative assessment of images and clinical adjudication when relevant. Individuals with end-stage renal failure or contraindications to MRI were excluded. Participants also underwent detailed recording of symptoms, and physiological and biochemical tests. The primary outcome was the excess burden of multiorgan abnormalities (two or more organs) relative to controls, with further adjustments for potential confounders. The C-MORE study is ongoing and is registered with ClinicalTrials.gov, NCT04510025. Findings: Of 2710 participants in Tier 2 of PHOSP-COVID, 531 were recruited across 13 UK-wide C-MORE sites. After exclusions, 259 C-MORE patients (mean age 57 years [SD 12]; 158 [61%] male and 101 [39%] female) who were discharged from hospital with PCR-confirmed or clinically diagnosed COVID-19 between March 1, 2020, and Nov 1, 2021, and 52 non-COVID-19 controls from the community (mean age 49 years [SD 14]; 30 [58%] male and 22 [42%] female) were included in the analysis. Patients were assessed at a median of 5·0 months (IQR 4·2–6·3) after hospital discharge. Compared with non-COVID-19 controls, patients were older, living with more obesity, and had more comorbidities. Multiorgan abnormalities on MRI were more frequent in patients than in controls (157 [61%] of 259 vs 14 [27%] of 52; p<0·0001) and independently associated with COVID-19 status (odds ratio [OR] 2·9 [95% CI 1·5–5·8]; padjusted=0·0023) after adjusting for relevant confounders. Compared with controls, patients were more likely to have MRI evidence of lung abnormalities (p=0·0001; parenchymal abnormalities), brain abnormalities (p<0·0001; more white matter hyperintensities and regional brain volume reduction), and kidney abnormalities (p=0·014; lower medullary T1 and loss of corticomedullary differentiation), whereas cardiac and liver MRI abnormalities were similar between patients and controls. Patients with multiorgan abnormalities were older (difference in mean age 7 years [95% CI 4–10]; mean age of 59·8 years [SD 11·7] with multiorgan abnormalities vs mean age of 52·8 years [11·9] without multiorgan abnormalities; p<0·0001), more likely to have three or more comorbidities (OR 2·47 [1·32–4·82]; padjusted=0·0059), and more likely to have a more severe acute infection (acute CRP >5mg/L, OR 3·55 [1·23–11·88]; padjusted=0·025) than those without multiorgan abnormalities. Presence of lung MRI abnormalities was associated with a two-fold higher risk of chest tightness, and multiorgan MRI abnormalities were associated with severe and very severe persistent physical and mental health impairment (PHOSP-COVID symptom clusters) after hospitalisation. Interpretation: After hospitalisation for COVID-19, people are at risk of multiorgan abnormalities in the medium term. Our findings emphasise the need for proactive multidisciplinary care pathways, with the potential for imaging to guide surveillance frequency and therapeutic stratification

    Serving diverse students in Canadian higher education

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    Comprend des références bibliographiques et un index.In recent decades, the Canadian post-secondary education system has evolved to become more inclusive, now welcoming groups historically excluded from its many opportunities. Inviting the reader to explore the consequences of a rapidly changing student population, Serving Diverse Students in Canadian Higher Education presents new thinking about how education in general, and student services in particular, should be designed and delivered. A follow-up to Donna Hardy Cox and C. Carney Strange's Achieving Student Success (2010), this volume focuses on the best programs and practices in Canadian colleges and universities to improve the educational experiences of students who are Indigenous, people of colour, francophone, LGBTQQ, disabled, and adult learners, as well as international and first-generation students. Presenting findings obtained from both personal insight and relevant research, higher education practitioners and scholars from across the country detail the characteristics, concerns, and specific needs of each diverse group, to conclude that the success of these new students and the future of Canadian society depends on its post-secondary institutions'capacities to acknowledge students'differences, capitalize on their gifts, and accommodate them accordingly. Exploring the enriching breadth of university communities, Serving Diverse Students in Canadian Higher Education focuses on a new paradigm of individual differences and student success

    Datasets for "A cluster-randomised controlled trial of the LifeLab education intervention to improve health literacy in adolescents"

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    This dataset supports the publication: Woods-Townsend, Kathryn et al. (2021). A cluster-randomised controlled trial of the LifeLab education intervention to improve health literacy in adolescents. PLOS ONE The dataset contains the answers to the original questions asked of the adolescents in this trial and derived variables needed for the analysis. A few variables have been removed from the original dataset, such as date of birth, to preserve confidentiality. Three versions of the dataset are available: an SPSS portable file (.por); a Stata data file (.dta); and an SPSS data file (.sav).</span

    &apos;You are taking who?! to a national conference on social policy?&apos;: A place for youth in the social policy life of their communities

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    Abstract The Canadian province of Newfoundland and Labrador over the past fifteen years has experienced failure of the ground fish industry, high unemployment, eroding infrastructure, and ensuing high levels of outmigration falling upon an already small population spread over extensive geography. These factors have resulted in the &apos;leaving behind&apos; of those with the least capacity to relocate and market themselves in more economically viable areas. Most vulnerable are the youth left behind in rural and remote areas of the province, suggesting a focus on community capacity building as an apt response to this phenomenon as a means to maximize the sustainability of such communities into the future. The article describes a two-phase research project undertaken by three faculty members at the School of Social Work at Memorial University of Newfoundland, in partnership with several youth-serving agencies and funded by the federal government. On the basis of the belief that augmenting youths&apos; understanding of the role and shaping of social policy can increase their capacity for future meaningful community participation, the purpose of the research was to advance knowledge about factors that influence engagement of youth in community-based social policy activity. Analysis of the findings is presented in terms of the factors that impede youth engagement in th
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